I've recently been trying out D-Aspartic acid at a dosage at 4000mg a day, the first 5-10 days of taking the supplement I didn't notice much at all but once it crossed over the 10 day mark of taking DAa, I started to notice my muscles were feeling fuller throughout the day along with an increased libido.
With this come pretty bad headaches, my throat also felt a bit swollen, and insomnia set in where I just couldn't switch off, just to make sure I did stop taking DAa and since then the headaches have gone, my swollen throat has started to go down, and I’m sleeping again...
Has anybody else experienced side effects with this supplement??
And for those who don't know anything about the supplement yet, a little write up below from another site:
D-Aspartic acid is an amino acid present in Neuroendocrine tissues, invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this amino acid on the release of LH and testosterone in the serum of humans and rats. Furthermore, we investigated the role of D-aspartate in the synthesis of LH and testosterone in the pituitary and testes of rats, and the molecular mechanisms by which this amino acid triggers its action.
For humans: A group of 23 men were given a daily dose of D-aspartate (DADAVIT ®) for 12 days, whereas another group of 20 men were given a placebo. For rats: A group of 10 rats drink a solution of either 20 mM D-aspartate or a placebo for 12 days. Then LH and testosterone accumulation was determined in the serum and D-aspartate accumulation in tissues. The effects of D-aspartate on the synthesis of LH and testosterone were gauged on isolated rat pituitary and Leydig cells. Tissues were incubated with D-aspartate, and then the concentration (synthesis) of cGMP in the pituitary and LH and of testosterone and cAMP in the Leydig cells was determined.
In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release. In the rat pituitary, sodium D-aspartate increases the release and synthesis of LH through the involvement of cGMP as a second messenger, whereas in rat testis Leydig cells, it increases the synthesis and release of testosterone and cAMP is implicated as second messenger. In the pituitary and in testes D-Asp is synthesized by a D-aspartate racemase which convert L-Asp into D-Asp. The pituitary and testes possesses a high capacity to trapping circulating D-Asp from hexogen or endogen sources.
D-aspartic acid is a physiological amino acid occurring principally in the pituitary gland and testes and has a role in the regulation of the release and synthesis of LH and testosterone in humans and rats.